An S-Class rogue ninja of Konohagakure, Sasuke Uchiha's older brother and prominent member of Akatsuki.
In the English dub version of the Naruto anime, Itachi made his speaking debut in episodes 29 and 30 in a flashback. In those episodes he was voiced by Skip Stellrecht. For episode 80 onwards he is voiced by Crispin Freeman. Freeman reprises the role in the English dub of Naruto: Shippuden.