Shinsuke Takasugi is the leader of the Kihetai (an extremist Joi faction) and one of the main antagonists of Gintama. Along with Gintoki Sakata and Kotaro Katsura, Takasugi studied under Shoyo Yoshida in his youth. During the Joi War, he fought alongside Gintoki, Katsura, and Tatsuma Sakamoto. However, after Shoyo's death, Takasugi became extremely bitter and resolves to destroy the world that killed his beloved sensei. His charisma has drawn many to his side, joining him in his quest to destroy the Shogunate... and Gintoki himself.
When Sentai Filmworks dubbed the Benizakura compilation movie, voice director Kyle Jones played Takasugi. For the Ocean dub of the third series, Alex Zahara would voice him. In the 2019 Universal Cinergia dub, Takasugi was voiced by Donald Guzzi.