Kyosuke Isazu is the main antagonist of A.I.C.O. -Incarnation-. An intelligent researcher, Kyosuke descended into madness when he was unable to save his only daughter, Yuzuha, after she fell into a coma. He tries to use the Matter to create clones of his daughter to be with her once again.
In the Studios VOA dub, Isazu was voiced by Sahid Pabon. For Bang Zoom's redub, he was instead voiced by Ray Chase (under an alias, Sam Ryder).